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Drug Design Data Resource Grand Challenge 3 Dataset: VEGFR2
Vascular endothelial growth factor receptor 2 (VEGFR2) is fundamental for vascular endothelial cell development. It is involved in tumor angiogenesis and diabetic retinopathy. The tyrosine kinase domain of VEGFR-2 has been an attractive drug target for a number of pharmaceutical companies with the aim to block its downstream intracellular signaling pathways. This effort has resulted in multiple tyrosine kinase inhibitors. It is based on dissociation constants (Kd) for 85 diverse ligands.
Data Files
| File Name | Description | Date Added | Download |
|---|---|---|---|
| GC3_VEGFR2.zip | VEGFR2 Dataset from Grand Challenge 3 | 03:39pm February 6, 2020 | Download |
Document Files
| File Name | Description | Date Added | Download |
|---|---|---|---|
| No Document Files |
About
Welcome to the Drug Design Data Resource Community. D3R is funded in part by NIH grant 1U01GM111528 from the National Institute of General Medical Sciences
