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Drug Design Data Resource Grand Challenge 3 Dataset: JAK2_SC2
Janus Kinase 2 (JAK2) is an intracellular protein tyrosine kinase that is critical to the mediation of cytokine signaling. Its dysregulation is involved in multiple diseases, including autoimmune diseases (rheumatoid arthritis and psoriasis), myeloproliferative syndromes (polycythemia vera, leukemias, and lymphomas), and cardiovascular diseases. It is based on dissociation constants (Kd) for 89 diverse ligands.
Data Files
| File Name | Description | Date Added | Download |
|---|---|---|---|
| GC3_JAK2_SC2.zip | JAK_SC2 Dataset from Grand Challenge 3 | 03:44pm February 6, 2020 | Download |
Document Files
| File Name | Description | Date Added | Download |
|---|---|---|---|
| No Document Files |
About
Welcome to the Drug Design Data Resource Community. D3R is funded in part by NIH grant 1U01GM111528 from the National Institute of General Medical Sciences
