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AbbVie-CSAR HSP90
The HSP90 dataset, kindly donated by Abbvie, was expanded and curated by the CSAR group at University of Michigan. The ATP site of HSP90 has been the subject of many oncology drug discovery programs over the past 15 years and consequently has a large representation in the PDB and literature. However, the prevalence of water-mediated ligand protein-interactions and a ligand binding site that accesses multiple open and closed pocket conformations can make estimation of docking pose and ranked affinity a challenge. (http://dx.doi.org/10.15782/D6159W)
Data Files
| File Name | Description | Date Added | Download |
|---|---|---|---|
| HSP90-CDD Export - 2016-08-31.xls | HSP90 datafile from the D3R Grand Challenge 2015 | 08:57am September 2, 2016 | Download |
Document Files
| File Name | Description | Date Added | Download |
|---|---|---|---|
| No Document Files |
About
Welcome to the Drug Design Data Resource Community. D3R is funded in part by NIH grant 1U01GM111528 from the National Institute of General Medical Sciences
